Vol 22, No 1 (2017)

88 sera from patients with dengue fever were examined with the use of two test systems: Pilot Production kit «ELISA- IgM-dengue», delivered in the D.I. Ivanovsky Institute of Virology (Russian Federation) and. All 88 samples were positive for specific IgM in «ELISA-IgM-dengue», but 8 cases examined with the test kit «Anti-Dengue virus ELISA (IgM)» (Euroimmun, Germany) appeared to be negative. The ratio between the titers of anti-dengue IgM determined in patients’ blood samples by "ELISA-IgM-dengue" and «Ratio» (index, recommended by the company «Euroimmun» for differentiation of positive, equivocal or negative results, was evaluated. 53 blood sample containing M antibodies to cytomegalovirus (n = 43), Epstein-Barr virus (n = 6), herpes simplex virus (n = 2) and rubella virus (n = 2) were tested by both ELISA kits to compare their specificity. When «ELISA- IgM-dengue» kits were applied all observed samples were negative, but under the application of the «Anti-Dengue virus ELISA (IgM)» kit (Euroimmun, Germany) 17 samples (32.1%) were false positive or equivocal.

The territory of the Transbaikalian Krai is characterized by a wide spectrum of factors and conditions forming both external (probability of importation) and internal (local cases) epidemiological risks for occurrence of infectious diseases capable to cause the Public Health emergency situations. Hence, for the effective preventive and anti-epidemic measures the differentiated approach at municipal level is required. In the present work the systematization of epidemiological risks in the Transbaikalian Krai as in a whole and for the each municipal area was performed with the use of the previously proposed technique for the differentiation of the subject in the Russian Federation. On the basis of this systematization the reasonable target impact on the dominating risks to minimize the most probable reasons for emergency situations occurrence in Public Health services was proposed at the level of the municipal administration. Thus, the comprehensive estimation of epidemiological risks in Transbaikalian Krai permits to formulate the well-founded suggestions for the improvement of epidemiological surveillance for the infectious diseases capable to cause emergency situations in Public Health services.

Patients underwent many surgical interventions are referred to a high risk group on morbidity by viral hepatitis. Mixt replications of viruses of hepatitis В (VHB) and С occur rarely. Obstetricians and gynaecologists fail to recommend the implementation of IVF procedure for women with the burdened gynaecological history due to viral hepatitis В and С and the pronounced fibrosis of liver tissue. We showed that for such patients antiviral therapy (AVT) started in good time allows to stop the replication of virus of hepatitis C, considerably to decline the VHВ loading and diminish the activity of process of fibrogenesis that, consequently, gives a chance for performance of IVF procedure.

In the article there is presented the life and career of a prominent domestic epidemiologist and microbiologist, the talented organizer of health care, well-known public figure, a wonderful teacher, professor, Medical Service Colonel Victor Mikhailovich. Berman.