The bacterial and fungal microflora of the nail plate in patients with atopic dermatitis



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The microflora of affected nail plates was studied in atopic dermatitis patients with suspected onychomycosis. All the examined nail samples were shown to contain microorganisms inside keratinocytes in a group of 4 adults aged 24-35 years and 20 children aged 0.3-15 years. Two of the 24 subjects were found to have only mycotic elements; 2 had only gram-positive bacteria; the other 20 had mixed microflora. Eighteen subjects were ascertained to have yeast blastospores and 4 had dermatophyte elements. It was shown that there was no correlation between the bacterial and fungal contamination of samples (p = 0.006).
Whether it is necessary to design new topical agents to treat concomitant bacterial and fungal lesions of the nail plate is discussed in the paper.

作者简介

Vera Arzumanyan

Email: instmech@iitp.ru

T Kabaeva

N Vartanova

V Arzumanyan

I. I. Mechnikov Research Institute of Vaccines and Sera, Russian Academy of Medical Sciences

I. I. Mechnikov Research Institute of Vaccines and Sera, Russian Academy of Medical Sciences

T Kabayeva

Zhenes Regeneration Center, Moscow

Zhenes Regeneration Center, Moscow

N Vartanova

I. I. Mechnikov Research Institute of Vaccines and Sera, Russian Academy of Medical Sciences

I. I. Mechnikov Research Institute of Vaccines and Sera, Russian Academy of Medical Sciences

参考

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  2. Арзуманян В. Г., Кабаева Т. И., Латыпова М. Ф. Онихомикоз или онихобактериоз: дифференциальная диагностика и перспективы терапии // Пробл. мед. микол. - 2006. - № 1. - С. 24-26.
  3. McBride M. E., Freeman R. G., Knox J. M. Keratinophilic activity in species of Corynebacterium // Can. J. Microbiol. - 1970. - Vol. 16, N 10. - P. 1024-1025.
  4. Mikx F. H., de Jong M. H. Keratinolytic activity of cutaneous and oral bacteria // Infect. and Immun. - 1987. - Vol. 45, N 3. - P. 621-625.
  5. Rebell G., Taplin D. Dermatophytes. Their recognition and identification. - Maiami, 1971. - P. 124.

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