The bacterial and fungal microflora of the nail plate in patients with atopic dermatitis



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Abstract

The microflora of affected nail plates was studied in atopic dermatitis patients with suspected onychomycosis. All the examined nail samples were shown to contain microorganisms inside keratinocytes in a group of 4 adults aged 24-35 years and 20 children aged 0.3-15 years. Two of the 24 subjects were found to have only mycotic elements; 2 had only gram-positive bacteria; the other 20 had mixed microflora. Eighteen subjects were ascertained to have yeast blastospores and 4 had dermatophyte elements. It was shown that there was no correlation between the bacterial and fungal contamination of samples (p = 0.006).
Whether it is necessary to design new topical agents to treat concomitant bacterial and fungal lesions of the nail plate is discussed in the paper.

About the authors

Vera Georgievna Arzumanyan

Email: instmech@iitp.ru

T I Kabaeva

N O Vartanova

V G Arzumanyan

I. I. Mechnikov Research Institute of Vaccines and Sera, Russian Academy of Medical Sciences

I. I. Mechnikov Research Institute of Vaccines and Sera, Russian Academy of Medical Sciences

T I Kabayeva

Zhenes Regeneration Center, Moscow

Zhenes Regeneration Center, Moscow

N O Vartanova

I. I. Mechnikov Research Institute of Vaccines and Sera, Russian Academy of Medical Sciences

I. I. Mechnikov Research Institute of Vaccines and Sera, Russian Academy of Medical Sciences

References

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  2. Арзуманян В. Г., Кабаева Т. И., Латыпова М. Ф. Онихомикоз или онихобактериоз: дифференциальная диагностика и перспективы терапии // Пробл. мед. микол. - 2006. - № 1. - С. 24-26.
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  4. Mikx F. H., de Jong M. H. Keratinolytic activity of cutaneous and oral bacteria // Infect. and Immun. - 1987. - Vol. 45, N 3. - P. 621-625.
  5. Rebell G., Taplin D. Dermatophytes. Their recognition and identification. - Maiami, 1971. - P. 124.

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