Regularities of changes in laboratory parameters in patients with A/H1N1 influenza pneumonia

Elena Nikolaevna Romanova; Романова Елена Николаевна; Ol'ga Mikhaylovna Serebryakova; Серебрякова Ольга Михайловна; Anatoliy Vasil'evich Govorin; Говорин Анатолий Васильевич; Andrey Petrovich Filev; Филев Андрей Петрович; E N Romanova; Romanova E N; O M Serebryakova; Serebryakova O M; A V Govorin; Govorin A V; A P Filev; Filev A P

doi:10.17816/EID40561

Regularities of changes in laboratory parameters in patients with A/H1N1 influenza pneumonia

Authors: Romanova E.N.¹, Serebryakova O.M.¹, Govorin A.V.¹, Filev A.P.¹, Romanova EN², Serebryakova OM³, Govorin AV², Filev AP²
Affiliations:
2. Chita State Medical Academy, Ministry of Health and Social Development
3. Town Clinical Hospital One
Issue: Vol 16, No 4 (2011)
Pages: 23-27
Section: Articles
URL: https://rjeid.com/1560-9529/article/view/40561
DOI: https://doi.org/10.17816/EID40561
ID: 40561

Cite item

Abstract

The medical records of 97 patients with A/H1N1 influenza pneumonia were analyzed. The important feature of the disease is a high risk of fatal outcomes, the direct cause of which is acute respiratory distress syndrome (ARDS). The most significant abnormalities of laboratory values were noted in this category of patients. In ARDS, leukopenia or normocytosis changed to leukocytosis, which is attributed to massive bacterial infection. These patients were also recorded to have immunodeficiency-induced lymphopenia and disseminated intravascular coagulation-induced thrombocytopenia. The marked elevation of transaminases mainly due to asparagine transaminase and the increase of creatine phosphokinase suggest that the most severe category of patients has rhabdomyolysis. Characteristic of this was a reactive rise of amylase. In ARDS, diminished renal functional capacity reflected the higher blood levels of creatinine and urea.

Keywords

community-acquired pneumonia, A/H1N1 influenza, acute lung injury, acute respiratory distress syndrome

References

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Regularities of changes in laboratory parameters in patients with A/H1N1 influenza pneumonia

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