Efficiency of antiretroviral therapy for HIV infection



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Abstract

The authors give the results of studying the efficiency of standard highly active antiretroviral therapy (HAART) regiments in patients with HIV infection. The findings suggest that longevity in HIV-infected patients receiving HAART is 2 times higher than in untreated patients. At the same time, the best treatment results were obtained at the beginning of HAART in patients with higher CD4+ lymphocyte levels and the choice of the first therapy regimen failed to affect therapeutic effectiveness. The change of the first treatment regimen was mainly associated with adverse reactions. Treatment was ineffective in only 1.4% of cases due to the developed resistance to antiviral agents.

About the authors

G F Moshkovich

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

S V Minayeva

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

Email: mistella@yandex.ru
Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

L V Varlova

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

M P Goryaeva

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

I D Voronina

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

Ye V Tikhonova

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

Nizhni Novgorod Regional Center for Prevention and Control of AIDS and Infectious Diseases, Nizhni Novgorod

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