Clinical presentation and some parameters of nonspecific resistance in Q-fever



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The paper presents the results of a clinical observation and complex examination of 48 patients with Q-fever, the blood samples from 20 of them were tested for lysozyme, complement, and circulating immune complexes (CIC). The swing of the disease was characterized by the maximum clinical manifestations of the disease. Early reconvalescence was marked by a decrement in the clinical symptoms of the disease and a gradual recovery of the body's impaired functions. The study indicated a relationship between the level of nonspecific resistance factors and the stage of the pathologic process. The swing of the disease showed an increase in the amount of CIC with lower complement activity and normal lysozyme levels. In early reconvalescence, there was an increase in the levels of CIC and a decrease in total complementary activity as compared with those in the previous period. At the same time blood lysozyme activity substantially increased and exceeded the control values.

作者简介

Svetlana Karpenko

Kh Galimzyanov

N Kasimova

O Rubal'skiy

I Vishnevetskaya

T Mikhaylovskaya

N Abdrakhmanova

S Karpenko

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

Kh Galimzyanov

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

N Kasimova

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

O Rubalsky

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

I Vishnevetskaya

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

Research Institute of Territorial Infectious Pathology, Astrakhan State Medical Academy

T Mikhailovskaya

Regional Infectious Diseases Clinical Hospital

Regional Infectious Diseases Clinical Hospital

N Abdrakhmanova

Centralized Laboratory of Clinical Microbiology (Bacteriology), City Children's Polyclinic One, Astrakhan

Centralized Laboratory of Clinical Microbiology (Bacteriology), City Children's Polyclinic One, Astrakhan

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