Monitoring results of the incidence of non-polio enterovirus infection in the pre-pandemic and pandemic periods

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Abstract

BACKGROUND: The study presents the results of monitoring the incidence of non-polio enterovirus infection in the pre-pandemic and pandemic periods in Khanty–Mansi Autonomous Okrug–Yugra (2011–2021).

AIM: To analyze the incidence of non-polio EVI in the urban population of Khanty–Mansi Autonomous Okrug–Yugra for 2011–2021.

MATERIALS AND METHODS: A retrospective analysis of the manifestations of the epidemic process of non-polio enterovirus infection was conducted, and the results of virological monitoring were presented.

RESULTS: The total incidence of EVI was predominantly shared by the urban population with predominance of children aged <6 years and school children. In the period 2020–2021, the low incidence of EVI was due to ongoing anti-epidemic measures against COVID-19 and was accompanied by the spread of enterovirus CVA6 serotype, which can effectively implement the aspiration mechanism of the transmission of the infectious agent and cause respiratory and exanthemic diseases. The spread of CVA6 was affected by an increase in the migration activity of the population, due to the partial lifting of restrictions and an increase in the non-immune stratum of the population and a decrease in the incidence of EVI in 2020. The results of the study will contribute to the adoption of measures leading to a decrease in the incidence of EVI in the Khanty–Mansiysk Autonomous Okrug and rational planning of preventive measures by improving the information and diagnostic subsystems of epidemiological surveillance.

CONCLUSION: To solve the tasks, further investigation of the spectrum of enteroviruses circulating in the Khanty–Mansiysk Autonomous Okrug, frequency of their occurrence in subclinical forms of EVI and as etiological agents of enteroviral meningitis, development of a molecular genetic typing technique using the technology of mass parallel high-throughput sequencing, and study of molecular genetic characteristics is necessary. These will reduce the risks of EVI in the post-pandemic period, ensure the sanitary and epidemiological well-being of the population, and prevent EVI spread in the Khanty–Mansiysk Autonomous Okrug.

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About the authors

Ekaterina A. Danshina

Center for Hygiene and Epidemiology in Khanty-Mansiysk Autonomous Okrug-Yugra; Surgut State University, Surgut

Email: kotya9530@mail.ru
ORCID iD: 0000-0002-3382-2161
SPIN-code: 7042-3503
Russian Federation, Surgut; Surgut

Andrey Y. Mironov

Moscow Research Institute of Epidemiology and Microbiology named after G.N. Gabrichevsky; Academy of Postgraduate Education of the Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies

Email: andy.60@mail.ru
ORCID iD: 0000-0002-8544-5230
SPIN-code: 9225-1560

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow; Moscow

Tatiana Suranova

Academy of Postgraduate Education of the Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies

Email: suranovatatiana@mail.ru
ORCID iD: 0000-0003-3411-1027
SPIN-code: 7326-5273

MD, PhD, Professor of the Department of hygiene, epidemiology and infectious diseases, Academy of Postgraduate Education

Russian Federation, Moscow

Alexandr V. Kuyarov

Surgut State University

Author for correspondence.
Email: kujarov@mail.ru
ORCID iD: 0000-0001-8388-9607
SPIN-code: 4821-0912

Dr. Sci. (Med.), Professor

Russian Federation, Surgut

References

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  3. Golitsyna LN, Zverev VV, Selivanova SG, et al. Etiological structure of enterovirus infections in the Russian Federation in 2017–2018. Public Health and Life Environment – PH&LE. 2019;(8):30–38. (In Russ). doi: 10.35627/2219-5238/2019-317-8-30-38
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  7. Danshina EA, Kuyarov AV, Saigusheva LA, Kuyarov AA. The prevalence of enterovirus infection among residents of the urbanized North. Infectious diseases in the modern world: epidemiology, diagnosis, treatment and prevention. In: Pokrovsky VI, editor. Proceedings of the 12th Annual All-Russian Internet Congress on Infectious Diseases with International Participation. Moscow; 2020. P:67. (In Russ).
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  9. Nikiforov VV, Suranova TG, Mironov AYu, Zabozlaev FG. New coronavirus infection (COVID-19): etiology, epidemiology, clinic, diagnosis, treatment and prevention. Moscow: Academy of Postgraduate Education of the FNKTs FMBA of Russia; 2020. 55 p. (In Russ).
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Supplementary files

Supplementary Files
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1. Fig. 1. EVI incidence rates in the Russian Federation and KhMAO-Yugra from 2011 to 2021 per 100 thousand population.

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2. Fig. 2. EVI incidence rates of the urban population of the Khanty-Mansi Autonomous Okrug in 2013–2020 per 100 thousand population.

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