Dengue Fever in Pregnant Women (A Series of Clinical Cases)

Dengue fever (DF) is a zooanthroponotic vector-borne viral infectious disease caused by four antigenically different serotypes of dengue virus (DENV 1-4). This infection is prevalent in 128 countries with tropical and subtropical climate. Clinical manifestations of the disease are wide ranging from asymptomatic/mild to severe dengue such as dengue hemorrhagic fever or dengue shock syndrome. Pregnant women, who develop dengue, as well as their fetuses, are at high risk of developing various complications. Taking into consideration the data published by foreign authors, the most common complications in pregnant women with severe dengue include miscarriage, low birth weight, and premature birth. On the one hand, infection during the early stages of pregnancy does not cause fetal malformations or long-term consequences; on the other hand, it may lead to miscarriage in the first trimester. The article discusses two clinical cases of DF in pregnant women returning from a dengue-endemic area, such as Thailand, and both reported insect bites. The course of the disease was uncomplicated, and both patients recovered. Further observations showed that both pregnancies ended with the birth of full-term, healthy infants.