Email this article Generalized tetanus: a case report
- Authors: Shakhmardanov M.Z.1,2, Nikiforov V.V.1,2, Skryabina A.A.1, Burova S.V.1, Tomilin Y.N.1, Abusueva A.S.3, Antipyat N.A.4
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Affiliations:
- Pirogov Russian National Research Medical University, Ministry of health of Russia
- Academy of Postgraduate Education of the Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies
- Dagestan State Medical Academy
- Infectious Clinical Hospital No. 1
- Issue: Vol 27, No 4 (2022)
- Pages: 255-260
- Section: CASE REPORTS
- URL: https://rjeid.com/1560-9529/article/view/114801
- DOI: https://doi.org/10.17816/EID114801
- ID: 114801
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Abstract
Tetanus is a rare disease caused by Clostridium tetani, causing damage to the central nervous system with the development of muscle hypertension and attacks of generalized seizures caused by the action of the pathogenic toxin. Despite the availability of safe and effective vaccines, the urgency of the problem of tetanus incidence is high because a significant part of the population is not immunized against this disease, and severe manifestations of tetanus can be fatal.
This paper presents a clinical case of traumatic generalized tetanus in an 11-year-old patient. The absence of routine immunization against tetanus and emergency active–passive immunization contributed to disease development. The disease proceeded in a typical form, with the development of muscle spasms, myoclonia, trism, and convulsions. Specific tetanus serum was administered, pathogenetic therapy with anticonvulsants and muscle relaxants was performed, and the patient had clinical recovery and was discharged from the hospital.
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About the authors
Murad Z. Shakhmardanov
Pirogov Russian National Research Medical University, Ministry of health of Russia; Academy of Postgraduate Education of the Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies
Email: mur2025@rambler.ru
ORCID iD: 0000-0002-3168-2169
SPIN-code: 3312-4052
MD, Dr. Sci. (Med.), Professor
Russian Federation, 117997, Ostrovityanova str.1, Moscow; MoscowVladimir V. Nikiforov
Pirogov Russian National Research Medical University, Ministry of health of Russia; Academy of Postgraduate Education of the Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies
Email: v.v.nikiforov@gmail.com
ORCID iD: 0000-0002-2205-9674
SPIN-code: 9044-5289
MD, Dr. Sci. (Med.), Professor
Russian Federation, 117997, Ostrovityanova str.1, Moscow; MoscowAnna A. Skryabina
Pirogov Russian National Research Medical University, Ministry of health of Russia
Email: anna.skryabina.85@mail.ru
ORCID iD: 0000-0002-2098-222X
SPIN-code: 3692-6818
MD
Russian Federation, 117997, Ostrovityanova str.1, MoscowSvetlana V. Burova
Pirogov Russian National Research Medical University, Ministry of health of Russia
Email: svburova@list.ru
ORCID iD: 0000-0001-7664-7685
SPIN-code: 9165-2625
MD, Cand. Sci. (Med.), Associate Professor
Russian Federation, 117997, Ostrovityanova str.1, MoscowYuri N. Tomilin
Pirogov Russian National Research Medical University, Ministry of health of Russia
Email: papa220471@mail.ru
ORCID iD: 0000-0003-2767-4868
SPIN-code: 8938-2621
MD, Cand. Sci. (Med.)
Russian Federation, 117997, Ostrovityanova str.1, MoscowAida S. Abusueva
Dagestan State Medical Academy
Email: amur39@mail.ru
ORCID iD: 0000-0002-6999-1696
SPIN-code: 4713-7110
MD, Cand. Sci. (Med.), Associate Professor
Russian Federation, MakhachkalaNatalya A. Antipyat
Infectious Clinical Hospital No. 1
Author for correspondence.
Email: natadoc70@bk.ru
ORCID iD: 0000-0001-8578-2838
SPIN-code: 6105-6285
MD
Russian Federation, 117997, Ostrovityanova str.1, MoscowReferences
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