Traditional Uses, Phytochemical Constituents and Ethnopharmacological Properties of Mistletoe from Phoradendron and Viscum Species


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Plants from the genus Phoradendron and Viscum, also known as American and European mistletoe, are a group of hemiparasitic plants traditionally used to treat many diseases. Mistletoes have a rich content of natural compounds like terpenes, alkaloids, proteins, and phenolic compounds associated with their potential medicinal properties. In this sense, mistletoes have shown antiproliferative, antioxidant, anti-inflammatory, and antimicrobial activity, which has been attributed to their phytochemical constituents. The mechanisms in which mistletoe plants act vary and depend on their phytochemical content and distribution, which in part will depend on the mistletoe species. In this sense, recent literature research is needed to visualize state of the art in the ethnopharmacological potential of mistletoe. Thus, this literature review aims to systematically report recent studies (2010-2023) on the phytochemical characterization and bioactive studies of mistletoe plants, mainly the Viscum and Phoradendron genera. We gather recent information of 140 references selected in our research. Here we report that although there are several bioactivity studies of mistletoe species, bioavailability studies are still scarce, and the precise mechanisms of action are not fully known. We encourage that further studies include a systematic strategy to cover these areas of opportunity.

Об авторах

Luis Montoya-Inzunza

Laboratory of Functional Foods and Nutraceuticals, Centro de Investigación en Alimentación y Desarrollo

Email: info@benthamscience.net

J. Heredia

Laboratory of Functional Foods and Nutraceuticals, Centro de Investigación en Alimentación y Desarrollo

Email: info@benthamscience.net

Jayanta Patra

Research Institute of Integrative Life Sciences,, Dongguk University-Seoul

Email: info@benthamscience.net

Sushanto Gouda

Developmental Biology & Herpetology Laboratory, Department of Zoology, Mizoram University

Email: info@benthamscience.net

Rout Kerry

Department of Biotechnology, Utkal University

Email: info@benthamscience.net

Gitishree Das

Research Institute of Integrative Life Sciences, Dongguk University-Seoul

Email: info@benthamscience.net

Erick Gutierrez-Grijalva

Laboratory of Functional Foods and Nutraceutical, Cátedras CONACYT-Centro de Investigación en Alimentación y Desarrollo

Автор, ответственный за переписку.
Email: info@benthamscience.net

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