Epidemiology and Infectious DiseasesEpidemiology and Infectious Diseases1560-95292411-3026Eco-Vector4102810.18821/1560-9529-2018-23-6-274-278Research ArticleCOMPARATIVE EVALUATION OF THE EPIDEMIC PROCESS MANIFESTATIONS AND LEADING FACTORS OF SEROUS MENINGITIS PATHOGENSAND HERPETIC ANGINA OF ENTEROVIRAL ETIOLOGY TRANSMISSIONSergevninV. Iviktor-sergevnin@mail.ruTryasolobovaM. Atrjaslbva@rambler.ruDevyatkovM. Yuantroponoz@eandex.ruKuzovnikovaE. Zhantroponoz@eandex.ruPerm State Medical University named after Academician E.A. Wagner of the Ministry of Healthcare of the Russian FederationCenter of Hygiene and Epidemiology in Perm Region1512201823627427823072020Copyright © 2018, Eco-vector2018<p>The aim of the work is a comparative evaluation of the epidemic process manifestations and the leading factors of serous meningitis (SM) pathogens and enteroviral etiologyherpetic angina (HA) transmission. Materials and methods. Manifestations of the epidemic process of SM and HA were studied according to the official registration of the incidence of the population of Perm for the 2010-2016. 1464 water samples of the distribution network, 178 samples of water from decentralized sources of water system, 293 samples of surface water, 117 samples of bottled water, and 57 wipe samples from the surface of vegetables and fruits were studied usingpolymerase chain reaction (PCR)for the presence of markers of non-polyemic enteroviruses (NEV). In conditions of analytical case-control method the epidemiological survey of 350 epidemiological focuses of SM and 142 focuses of GA were conducted. Results. The findingsclearly demonstratethat it is similarity betweenepidemic process manifestations of SM and enteroviral etiologyHA. In both clinical variants of enteroviral infection, the priority role is the water way of transmission of the pathogen by drinking water from centralized and decentralized sources of water system, as well as swimming in surface water. The water transmission way is activated in the summer-autumn period of the year due to the increase in the number of emergency situations on the water supply networks, as well as due to the swimming factor. The role of bottled water as well as vegetables and fruits as factors of transmission of enteroviral infection has been revealed.</p>enteroviral infectionserous meningitisherpetic anginaepidemic process manifestationspathogen`s ways of transmissionэнтеровирусная инфекциясерозный менингитгерпетическая ангинапроявления эпидемического процессапути передачи возбудителя[Профилактика энтеровирусной (неполио) инфекции. СП 3.1.2950-11.][Эпидемиологический надзор и профилактика энтеровирусной (неполио) инфекции. МУ 3.1.1.2363-08.][Амвросьева Т. В., Поклонская Н.В., Зуева В.Л, Богуш З.Ф., Дедюля К.Л., Лукашев А.Н. Энтеровирусные инфекции в республике Беларусь. Эпидемиология и инфекционные болезни. 2014; 5: 37 - 43.][Сапега Е.Ю., Троценко О.Е., Резник В.И., Перескокова М.А., Каравянская Т.Н., Голубева Е.М. Анализ проявлений эпидемического процесса энтеровирусной инфекции в Дальневосточном регионе в 2010 году. Дальневосточный журнал инфекционной патологии. 2011; 19: 18 - 22.][Фомина С.Г., Новикова Н.А. Энтеровирусы у детей с гастроэнтеритом (аналитический обзор). Медиаль. 2014; 2 (12): 63 - 71.][Сейбиль В.Б., Малышкина Л.П. Энтеровирусы в ХХ и ХХI веках. Журнал микробиологии, эпидемиологии и иммунобиологии. 2005; 4: 83 - 9.][Организация и проведение вирусологических исследований материалов из объектов внешней среды на полиовирусы, другие (неполио) энтеровирусы. МУК 4.2.2357-08.][Санитарно-вирусологический контроль водных объектов. МУК 4.2.2029-05.][Руководство по лабораторным исследованиям полиомиелита. ВОЗ, Женева. 2005. 4-е издание.][Палтышев И.П., Герасимов А.Н. Методика определения сроков начала и окончания сезонных подъемов. Теор. пробл. эпидемиол. инфекц. иммунол. Тезисы докладов конф. г. Нальчик, 1986; 52 - 5.]