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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Epidemiology and Infectious Diseases</journal-id><journal-title-group><journal-title xml:lang="en">Epidemiology and Infectious Diseases</journal-title><trans-title-group xml:lang="ru"><trans-title>Эпидемиология и инфекционные болезни</trans-title></trans-title-group></journal-title-group><issn publication-format="print">3034-2007</issn><issn publication-format="electronic">3034-2015</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">108396</article-id><article-id pub-id-type="doi">10.17816/EID108396</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Cardiovascular pathology in HIV infection</article-title><trans-title-group xml:lang="ru"><trans-title>Кардиоваскулярная патология при ВИЧ-инфекции</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6892-4838</contrib-id><contrib-id contrib-id-type="spin">3110-0481</contrib-id><name-alternatives><name xml:lang="en"><surname>Tuaeva</surname><given-names>Renata G.</given-names></name><name xml:lang="ru"><surname>Туаева</surname><given-names>Рената Грантиковна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><email>121renata@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5033-2746</contrib-id><contrib-id contrib-id-type="spin">5889-7900</contrib-id><name-alternatives><name xml:lang="en"><surname>Loseva</surname><given-names>Olga K.</given-names></name><name xml:lang="ru"><surname>Лосева</surname><given-names>Ольга Казимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>loseva_ok@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5327-9824</contrib-id><contrib-id contrib-id-type="spin">6779-9405</contrib-id><name-alternatives><name xml:lang="en"><surname>Nagibina</surname><given-names>Margarita V.</given-names></name><name xml:lang="ru"><surname>Нагибина</surname><given-names>Маргарита Васильевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>infector03@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6565-7407</contrib-id><contrib-id contrib-id-type="spin">1859-2381</contrib-id><name-alternatives><name xml:lang="en"><surname>Bessarab</surname><given-names>Timur P.</given-names></name><name xml:lang="ru"><surname>Бессараб</surname><given-names>Тимур Петрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>bessarab@spid.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology</institution></aff><aff><institution xml:lang="ru">Московский научно-практический центр дерматовенерологии и косметологии</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Moscow City Center for AIDS Prevention and Treatment</institution></aff><aff><institution xml:lang="ru">Московский городской центр профилактики и борьбы со СПИД</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2022-06-27" publication-format="electronic"><day>27</day><month>06</month><year>2022</year></pub-date><pub-date date-type="pub" iso-8601-date="2021-05-15" publication-format="electronic"><day>15</day><month>05</month><year>2021</year></pub-date><volume>26</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>135</fpage><lpage>140</lpage><history><date date-type="received" iso-8601-date="2022-05-30"><day>30</day><month>05</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-06-20"><day>20</day><month>06</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Eco-vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, ООО "Эко-вектор"</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Eco-vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2024-05-15"/></permissions><self-uri xlink:href="https://rjeid.com/1560-9529/article/view/108396">https://rjeid.com/1560-9529/article/view/108396</self-uri><abstract xml:lang="en"><p>Currently, there are indications of an increase in the incidence of cardiovascular pathology in patients with HIV infection in comparison with population data and a higher mortality rate from cardiovascular diseases. The problem of detecting the pathology of the cardiovascular system in patients infected with the human immunodeficiency virus (HIV) is relevant due to the increase in the number of HIV-positive individuals and the established effect of HIV infection on the circulatory organs. In order to identify cardiovascular pathology, two patients with stages III and IV of HIV infection were extensively examined. The examination was carried out using electrocardiography, echocardiography and ultrasound dopplerography. Both clinical cases are presented below, in which pronounced cardiovascular pathology was detected in both cases. As factors influencing the development of pathology of the cardiovascular system, based on the presented clinical examples, drug addiction (long-term intravenous use of surfactants) and pathologies of other internal organs in the development of HIV-mediated opportunistic diseases are considered. Analysis of the course of the disease showed that the lesion can develop in various stages of HIV infection, more often infectious endocarditis is the main diagnosis in patients in stage 3 of HIV infection (the first clinical example), and dilated cardiomyopathy — in the late stages of HIV infection and is considered as a concomitant pathology due to lung and kidney damage (the second clinical example).</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время имеются указания на увеличение частоты развития сердечно-сосудистой патологии у больных ВИЧ-инфекцией (вирус иммунодефицита человека) в сравнении с популяционными данными и более высокий уровень летальности от сердечно-сосудистых заболеваний. Проблема выявления патологии сердечно-сосудистой системы у пациентов, инфицированных ВИЧ, является актуальной в связи с увеличением числа ВИЧ-позитивных лиц и установленным влиянием ВИЧ-инфекции на органы кровообращения. С целью выявления кардиоваскулярной патологии расширенно обследованы два пациента с III и IV стадиями ВИЧ-инфекции. Обследование проводилось с использованием методов электрокардиографии, эхокардиографии и ультразвуковой допплерографии. В обоих случаях выявлена выраженная кардиоваскулярная патология. В качестве факторов, влияющих на развитие патологии сердечно-сосудистой системы, на основании представленных клинических примеров рассматриваются наркозависимость (длительное внутривенное употребление психоактивных веществ) и патологии внутренних органов при развитии ВИЧ-опосредованных оппортунистических заболеваний. Анализ течения заболевания показал, что поражение может развиваться на различных стадиях ВИЧ-инфекции, чаще инфекционный эндокардит является основным диагнозом у пациентов на III стадии ВИЧ-инфекции (первый клинический пример), а дилатационная кардиомиопатия — на поздних стадиях ВИЧ-инфекции и рассматривается как коморбидно-сочетанная патология вследствие поражения лёгких, почек (второй клинический пример).</p></trans-abstract><kwd-group xml:lang="en"><kwd>HIV infection</kwd><kwd>cardiac pathology</kwd><kwd>case report</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ВИЧ-инфекция</kwd><kwd>кардиологическая патология</kwd><kwd>клинический случай</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">French AL, Gawel SH, Hershow R, et al. Trends in mortality and causes of death among women with HIV in the United States: a 10-year study. 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