Email this article The Reaction of Dinitrofluoroacetonitrile with Substituted Nitrile N-Oxides
- Authors: Tyrkov A.G.1, Yurtaeva E.A.2, Utyaganova E.V.2
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Affiliations:
- Tatishchev Astrakhan State University
- Pyatigorsk Medical and Pharmaceutical Institute – branch of Volgograd State Medical University
- Issue: Vol 61, No 5 (2025)
- Pages: 552-556
- Section: ЭКСПЕРИМЕНТАЛЬНЫЕ СТАТЬИ
- URL: https://rjeid.com/0514-7492/article/view/692386
- DOI: https://doi.org/10.31857/S0514749225050055
- ID: 692386
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Abstract
The reaction of dinitrofluoroacetonitrile with nitrile N-oxides leads to 3-aryl(methyl)-5-dinitrofluoromethyl-1,2,4-oxadiazoles. The interaction of 1,2,4-oxadiazoles with an alcohol solution of potassium hydroxide is accompanied by the elimination of the dinitrofluoromethyl group and leads to 3-aryl(methyl)-5-hydroxy-1,2,4-oxadiazoles and the potassium salt of aci-dinitrofluoromethane.
About the authors
A. G. Tyrkov
Tatishchev Astrakhan State University
Email: tyrkov@rambler.ru
pl. Shaumyana, 1, Astrakhan, 414000 Russia
E. A. Yurtaeva
Pyatigorsk Medical and Pharmaceutical Institute – branch of Volgograd State Medical Universityprosp. Kalinina 11, Pyatigorsk, 357532 Russia
E. V. Utyaganova
Pyatigorsk Medical and Pharmaceutical Institute – branch of Volgograd State Medical Universityprosp. Kalinina 11, Pyatigorsk, 357532 Russia
References
- Фокин А.В., Студнев Ю.Н., Рапкин А.И., Кузнецо- ва Л.Д., Комаров В.А. Изв. АН СССР, сер. хим. 1976, 3, 489–492.
- Злотин С.Г., Варнаева Г.Н., Лукьянов О.А. Усп. химии. 1989, 53, 796–811.
- Yurtaeva E.A., Tyrkov A.G. Russ. J. Org. Chem. 2024, 60, 1251–1254 doi: 10.1134/S1070428024070169
- Тырков А.Г. ЖОрХ. 2002, 38, 1269–1270. [Tyr- kov A.G. Russ. J. Org. Chem. 2002, 38, 1815–1816.] doi: 10.1023/A:1020934400960
- Граник В.Г. Основы медицинской химии. М.: Вузовская книга, 2001, 188.
- Фокин А.В., Галахов В.С., Узун А.Т., Радченко В.П., Столяров В.П. Изв. АН СССР, сер. хим. 1974, 2, 456–458.
- Rheinboldt H. Annales de chimie. 1927, 451, 161–178.
- Harada K., Kaji E., Zen S. Chem. Pharm. Bull. 1980, 28, 3296–3303.
- Кирхнер Ю. Тонкослойная хроматография. М.: Мир, 1981, 1, 129, 218.
- Adams P., Kaiser D.W., Peters G.A. J. Org. Chem. 1953, 18, 934–941.
- Хуторецкий А.В., Охлобыстина Л.В., Файнзиль- берг А.Л. Изв. АН СССР, сер. хим. 1970, 2, 387‒392.
- Тырков А.Г. Дис. … докт. хим. наук, Саратов, 2005.
- Kamiya M.Y. Chem. Soc. Jap. 1970, 43, 3344–3353.
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